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抗菌薬
∼古典的RPG風∼
RPGって?
RPGとは、Role Playing Gameの略で、
ゲーム内のキャラクターになりきって
物語を進行していくカテゴリー
一般的に、フィールドを歩いていると
敵に遭遇し 戦闘画面に切り替わる
       というパターンをとる。
RPGって?
フィールド画面の例
フィールドを歩いている
やがて敵に出くわします
敵が 現れた !!
インベーダー 3ひき
 
▶ こうげき
  まほう
ぼうぎょ
どうぐ
ゆうしゃ
HP 72
MP 18
Lv.24
インベーダー 3ひき
 
▶ こうげき
  まほう
ぼうぎょ
どうぐ
ゆうしゃ
HP 72
MP 18
Lv.24
コマンドを⼊⼒して
次の⾏動を指⽰
ゆうしゃ
HP 72
MP 18
Lv.24
ゆうしゃは、インベーターAに こうげき!
47のダメージ!
ゆうしゃ
HP 72
MP 18
Lv.24
ゆうしゃは、インベーターAに こうげき!
47のダメージ!
インベーターAをたおした!!!
ゆうしゃ
HP 72
MP 18
Lv.24
インベーターBはまほうをつかった!
「イオナ●ン!!」
ゆうしゃ
HP 13
MP 18
Lv.24
インベーターBはまほうをつかった!
「イオナ●ン!!」
ゆうしゃに59のダメージ
ゆうしゃ
HP 13
MP 18
Lv.24
インベーターBはまほうをつかった!
「イオナ●ン!!」
ゆうしゃに59のダメージ
こんな感じで
戦闘が進んでいきます
そろそろ話は本題…
抗菌薬のスライドということで、
今回はRPGの「魔法」に喩えて
抗菌薬を一緒に勉強していきましょう。
話は本題…
ドラ■エの魔法(呪文)を例にとると、
こんな感じになります。
古典的ド■クエの呪文体系
メ■ 系 火炎の呪文
ヒ◆ド 系 氷の呪文
デ●ン系 雷の呪文
 etc.
どうして こんなに
呪文の種類がある?
敵によって
効く魔法、効かない魔法が
あるじゃない!
例えば
例えば
この中で、氷の呪文に弱そうなモンスターは?
例えば
この中で、氷の呪文に弱そうなモンスターは?
⾊的に
冷気が弱点
っぽい
例えば
赤いのを倒したければ、
氷の呪文で攻めるのがセオリー
⾊的に
冷気が弱点
っぽい
ここで重要なのが…
その魔法が(例えば氷の呪文)
どのモンスターに効きやすく、
どのモンスターに効きにくいか、
という知識。
ここで重要なのが…
そのモンスターに
効きやすい魔法は何か?
効きにくい魔法は何か?
という知識。
本題!!
モンスター = 原因微生物
攻撃魔法 = 抗菌薬
このように置き換えると、
抗菌薬が理解しやくなるかも
take home message
□ 感染源はどこか?
□ 推定される原因微生物は?
□ Gram染色が極めて有効!!
□ 適切な抗生剤は?
□ 治療効果判定の指標は?
メタファー(比喩)
しちゃいます!
ぼうけん してみる?
ぼうけん してみる?
舞台はラング王国へ
ラング王国らへんを歩いていると…
ラング王国らへんを歩いていると…
このへん
敵が 現れた !!
正体不明 (3+)
どうする?
 
診察
  検査
治療
経過観察
正体不明 (3+)
どうする?
 
▶ 診察
  検査
治療
経過観察
診察)体温 38.8℃、呼吸数 28/min、脈拍 132/min
肺:右側胸部でCoarse Crackleを聴取
黄色の膿性痰を吸引できた。
どうする?
 
診察
▶ 検査
治療
経過観察
正体不明 (3+)
BP 140/74
PR 132 reg
RR 28
BT 38.8
どうする?
 
診察
▶ 検査
治療
経過観察
正体不明 (3+)
グラム染色を施行 !! BP 140/74
PR 132 reg
RR 28
BT 38.8
どうする?
 
診察
▶ 検査
治療
経過観察
正体不明 (3+)
グラム染色を施行 !! BP 140/74
PR 132 reg
RR 28
BT 38.8
検査)痰のグラム染色を行った。
白血球の貪食像を伴うGPCを認めた!
Day 1
BP 140/74
PR 132 reg
RR 28
BT 38.8
検査)痰のグラム染色を行った。
白血球の貪食像を伴うGPCを認めた!
莢膜を伴うグラム陽性双球菌であった。
Day 1
BP 140/74
PR 132 reg
RR 28
BT 38.8
どうする?
 
診察
検査
▶ 治療
経過観察
肺炎球菌 (3+)
BP 140/74
PR 132 reg
RR 28
BT 38.8
Day 1
治療)ペニシリンG 1200万単位 分6の投与を開始!
Day 1
BP 140/74
PR 132 reg
RR 28
BT 38.8
治療)ペニシリンG 1200万単位 分6  2日目
Day 2
BP 128/70
PR 104 reg
RR 22
BT 38.9
治療)ペニシリンG 1200万単位 分6  3日目
Day 3
BP 130/72
PR 96 reg
RR 18
BT 37.6
どうする?
 
診察
▶ 検査
治療
経過観察
肺炎球菌 (3+)
BP 130/72
PR 96 reg
RR 18
BT 37.6
Day 3
どうする?
 
診察
▶ 検査
治療
経過観察
肺炎球菌 (3+)
BP 130/72
PR 96 reg
RR 18
BT 37.6
Day 3
グラム染色を施行 !!
BP 130/72
PR 96 reg
RR 18
BT 37.6
Day 3
検査)痰のグラム染色を行った。
GPCの数は減っている。
WBCの数は著変なし。
どうする?
 
▶ 診察
検査
治療
経過観察
肺炎球菌 (1+)
BP 130/72
PR 96 reg
RR 18
BT 37.6
Day 3
BP 130/72
PR 96 reg
RR 18
BT 37.6
Day 3
診察)呼吸苦の改善、食欲の回復を認めた。
Coarse Crackle消失、痰は白色の粘液性
咳の頻度は明らかに減って来ている。
BP 130/72
PR 96 reg
RR 18
BT 37.6
Day 3
∼細菌検査室よりの報告∼
入院時喀痰培養:WBC貪食像を伴うGPC(3+)
肺炎球菌であることが判明。
どうする?
 
診察
検査
治療
▶ 経過観察
肺炎球菌 (1+)
BP 128/68
PR 82 reg
RR 16
BT 37.2
Day 4
BP 110/60
PR 74 reg
RR 12
BT 36.7
Day 7
一週間、抗生剤の投与を継続したところ、
全身状態の改善あり。検査/画像上も増悪は無い。
BP 110/60
PR 74 reg
RR 12
BT 36.7
Day 7
 肺炎球菌をたおした!!
BP 110/60
PR 74 reg
RR 12
BT 36.7
Day 7
 無事退院 774の経験値を獲得!
 保険点数2652点
まとめ
take home message
□ 感染源はどこか?
□ 推定される原因微生物は?
□ Gram染色が極めて有効!!
□ 適切な抗生剤は?
□ 治療効果判定の指標は?
おしまい♪

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抗菌薬 ~古典的RPG風~