4. NORMAL SPLEEN
Normal size – 12 cm length , 7 cm width
(radionuclide scan)
-13cm craniocaudal diamtr (USG)
weight- < 250gm
Located along- 9th, 10th,11th ribs mid-axillary
Spleen should be twice the size to be PALPABLE
Palpable spleens are not always ABNORMAL
3% normal population has palpable spleen
6. FUNCTIONS
Quality control over RBC – culling & pitting
Synthesis of antibodies
Removal of antibody coated bacteria & RBC
12. DIFFERENCES
Sharp edge
Notch –med border
Cross midline
Moves with
respiration
Cannot get above it
Round edge
No notch
Not cross midline
Not moves with resp.
Can get above it
spleen kidney
35. TROPICAL SPLENOMEGALY (HMS)
Massive splenomegaly
Endemic areas of malaria,kala-azar
IgM antibodies +
No parasite in blood
Lymhocytic infiltration of splenic sinusoids
Long term anti-malarials
36. SUMMARY
Splenomegaly – major physical finding
Step wise approach- history,physical exam
Look for associated features
Lab investigation & Imaging
Search for etiology & treat